SNRNP40

Entrez Summary: N/A
UniProt Summary: Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs. {ECO:0000269|PubMed:9774689}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Gene	Correlation
PPIL1	0.464

Global Fraction of Cell Lines Where Essential: 265/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	12/28
blood	11/28
bone	7/26
breast	16/33
central nervous system	13/56
cervix	1/4
colorectal	9/17
esophagus	7/13
fibroblast	0/1
gastric	5/16
kidney	5/21
liver	5/20
lung	27/75
lymphocyte	5/16
ovary	12/26
pancreas	10/24
peripheral nervous system	7/16
plasma cell	8/15
prostate	0/1
skin	9/24
soft tissue	3/9
thyroid	0/2
upper aerodigestive	12/22
urinary tract	14/29
uterus	2/5

Expression Distribution