UniProt Summary: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Pfam DomainsGO Terms
Pfam Domains
TAS2R
GO Terms
taste receptor activity
bitter taste receptor activity
positive regulation of cytokinesis
detection of chemical stimulus involved in sensory perception of bitter taste
sensory perception of bitter taste
detection of chemical stimulus involved in sensory perception of taste
sensory perception of taste
positive regulation of cell division
regulation of cytokinesis
regulation of cell division
positive regulation of cell cycle process
positive regulation of cell cycle
detection of chemical stimulus involved in sensory perception
detection of chemical stimulus
sensory perception of chemical stimulus
detection of stimulus involved in sensory perception
detection of stimulus
G protein-coupled receptor activity
regulation of cell cycle process
sensory perception
regulation of cell cycle
G protein-coupled receptor signaling pathway
nervous system process
system process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)