Pfam Domains GO Terms
| Bax1-I |
| negative regulation of Fas signaling pathway |
| regulation of Fas signaling pathway |
| positive regulation of blood vessel remodeling |
| regulation of blood vessel remodeling |
| death receptor binding |
| negative regulation of protein localization to plasma membrane |
| negative regulation of protein localization to cell periphery |
| negative regulation of protein localization to membrane |
| positive regulation of tissue remodeling |
| negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| regulation of tissue remodeling |
| specific granule membrane |
| regulation of protein localization to plasma membrane |
| negative regulation of extrinsic apoptotic signaling pathway |
| negative regulation of cellular protein localization |
| regulation of protein localization to cell periphery |
| regulation of extrinsic apoptotic signaling pathway |
| regulation of protein localization to membrane |
| endosome membrane |
| negative regulation of apoptotic signaling pathway |
| lysosomal membrane |
| regulation of apoptotic signaling pathway |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| regulation of cellular protein localization |
| myeloid leukocyte activation |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| intracellular membrane-bounded organelle |
| regulated exocytosis |
| leukocyte mediated immunity |
| negative regulation of catalytic activity |
| exocytosis |
| negative regulation of apoptotic process |
| negative regulation of programmed cell death |
| regulation of cellular localization |
| leukocyte activation |
| Golgi apparatus |
| negative regulation of cell death |
| secretion by cell |
| regulation of protein localization |
| export from cell |
| regulation of anatomical structure morphogenesis |
| cell activation |
| immune effector process |
| secretion |
| negative regulation of molecular function |
| negative regulation of signal transduction |
| negative regulation of cell communication |
| negative regulation of signaling |
| regulation of apoptotic process |
| regulation of programmed cell death |
| negative regulation of response to stimulus |
| regulation of cell death |
| positive regulation of multicellular organismal process |
| immune response |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| All-trans-Retinoic-Acid 8μM R07 exp333 | -1.74 |
| JQ1 0.01μM R03 exp130 | 1.7 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution