UniProt Summary: Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis. {ECO:0000269|PubMed:12036294, ECO:0000269|PubMed:21552258}.
Pfam DomainsGO Terms
Pfam Domains
Translin
GO Terms
production of siRNA involved in RNA interference
RNA interference
endoribonuclease activity
dsRNA processing
production of small RNA involved in gene silencing by RNA
posttranscriptional gene silencing by RNA
posttranscriptional gene silencing
RNA phosphodiester bond hydrolysis, endonucleolytic
gene silencing by RNA
single-stranded DNA binding
gene silencing
RNA phosphodiester bond hydrolysis
regulation of gene expression, epigenetic
nucleic acid phosphodiester bond hydrolysis
sequence-specific DNA binding
posttranscriptional regulation of gene expression
spermatogenesis
male gamete generation
gamete generation
perinuclear region of cytoplasm
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
RNA processing
Golgi apparatus
multi-organism reproductive process
RNA binding
reproductive process
reproduction
DNA binding
RNA metabolic process
negative regulation of gene expression
gene expression
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)