Entrez Summary: The protein encoded by this gene may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane. Mutations in this gene cause the autosomal recessive disorder, chorea-acanthocytosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
Chorein N
DUF1162
ATG C
GO Terms
protein retention in Golgi apparatus
dense core granule
Golgi to endosome transport
protein localization to Golgi apparatus
protein targeting to vacuole
establishment of protein localization to vacuole
social behavior
intraspecies interaction between organisms
protein localization to vacuole
extrinsic component of membrane
multi-organism behavior
maintenance of protein location in cell
maintenance of location in cell
post-Golgi vesicle-mediated transport
maintenance of protein location
vacuolar transport
cytosolic transport
maintenance of location
locomotory behavior
process utilizing autophagic mechanism
autophagy
protein targeting
Golgi vesicle transport
establishment of protein localization to organelle
behavior
protein localization to organelle
intracellular protein transport
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
cellular catabolic process
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)