Pfam Domains GO Terms
| EGF |
| VWA |
| calcium-independent cell-matrix adhesion |
| growth plate cartilage chondrocyte morphogenesis |
| chondrocyte morphogenesis |
| chondrocyte morphogenesis involved in endochondral bone morphogenesis |
| growth plate cartilage morphogenesis |
| growth plate cartilage chondrocyte differentiation |
| chondrocyte development involved in endochondral bone morphogenesis |
| cartilage morphogenesis |
| chondrocyte differentiation involved in endochondral bone morphogenesis |
| growth plate cartilage development |
| endochondral bone growth |
| chondrocyte development |
| cartilage development involved in endochondral bone morphogenesis |
| bone growth |
| regulation of insulin receptor signaling pathway |
| regulation of cellular response to insulin stimulus |
| endochondral bone morphogenesis |
| chondrocyte differentiation |
| basement membrane |
| organ growth |
| bone morphogenesis |
| cell-matrix adhesion |
| cartilage development |
| cell-substrate adhesion |
| bone development |
| connective tissue development |
| extracellular matrix |
| skeletal system morphogenesis |
| protein homooligomerization |
| collagen-containing extracellular matrix |
| developmental growth |
| growth |
| skeletal system development |
| protein complex oligomerization |
| cell morphogenesis involved in differentiation |
| tissue morphogenesis |
| calcium ion binding |
| cell morphogenesis |
| cellular component morphogenesis |
| cell adhesion |
| biological adhesion |
| animal organ morphogenesis |
| identical protein binding |
| protein-containing complex assembly |
| extracellular space |
| cell development |
| tissue development |
| protein-containing complex subunit organization |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Cabazitaxel 0.001μM R05 exp223 | -1.96 |
| Tunicamycin 0.04 to 0.075μM on day4 R07 exp419 | 1.71 |
| Thalidomide 20μM R07 exp406 | 1.8 |
| Gene | Correlation |
|---|---|
| PRIM1 | 0.405 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution