Pfam Domains GO Terms
| Homeobox |
| cell fate determination |
| regulation of axon extension |
| regulation of extent of cell growth |
| neuron migration |
| positive regulation of translation |
| positive regulation of cellular amide metabolic process |
| regulation of cell size |
| regulation of axonogenesis |
| cell fate commitment |
| regulation of cell morphogenesis involved in differentiation |
| RNA polymerase II regulatory region sequence-specific DNA binding |
| regulation of developmental growth |
| regulation of translation |
| regulation of cellular component size |
| regulation of cellular amide metabolic process |
| regulation of cell growth |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| regulation of cell morphogenesis |
| regulation of neuron projection development |
| regulation of anatomical structure size |
| posttranscriptional regulation of gene expression |
| regulation of neuron differentiation |
| regulation of growth |
| regulation of plasma membrane bounded cell projection organization |
| regulation of cell projection organization |
| regulation of neurogenesis |
| regulation of nervous system development |
| regulation of cell development |
| cell migration |
| neuron differentiation |
| regulation of anatomical structure morphogenesis |
| localization of cell |
| cell motility |
| positive regulation of transcription by RNA polymerase II |
| locomotion |
| generation of neurons |
| positive regulation of transcription, DNA-templated |
| movement of cell or subcellular component |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| positive regulation of cellular protein metabolic process |
| neurogenesis |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| positive regulation of protein metabolic process |
| positive regulation of RNA metabolic process |
| tissue development |
| regulation of cell differentiation |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Cidofovir 10μM R07 exp345 | -1.98 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 1/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution