CCDC130

Gene Information

Official Symbol: CCDC130
Official Name: coiled-coil domain containing 130
Aliases and Previous Symbols: N/A
Entrez ID: 81576
UniProt: P13994
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
LY2090314 0.003μM R08 exp499	-2.78
LY2090314 0.003μM R08 exp500 no dilution day6	-2.6
Deferoxamine 11μM R07 exp350	-1.83
BI-6727 0.0125μM R03 exp97	-1.79
EPZ-5676 30μM R05 exp233	1.76
Milciclib 2μM R08 exp502	1.88
Phenformin 20μM R05 exp212	2.15

Gene	Correlation
ITFG2	0.486
NPRL2	0.485
C12orf66	0.485
NPRL3	0.473
SZT2	0.469
DEPDC5	0.454
ARID4B	0.429
SESN2	0.422
KPTN	0.415
WDR83	0.413
PDS5B	0.413

Global Fraction of Cell Lines Where Essential: 281/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	11/28
blood	5/28
bone	8/26
breast	21/33
central nervous system	10/56
cervix	1/4
colorectal	7/17
esophagus	9/13
fibroblast	0/1
gastric	7/16
kidney	8/21
liver	5/20
lung	36/75
lymphocyte	9/16
ovary	12/26
pancreas	15/24
peripheral nervous system	5/16
plasma cell	1/15
prostate	0/1
skin	6/24
soft tissue	1/9
thyroid	1/2
upper aerodigestive	17/22
urinary tract	12/29
uterus	1/5

Essentiality in NALM6

Essentiality Rank: 2146
Expression level (log2 read counts): 5.31

Expression Distribution