CCM2L
Gene Information
- Official Symbol: CCM2L
- Official Name: CCM2 like scaffold protein
- Aliases and Previous Symbols: N/A
- Entrez ID: 140706
- UniProt: Q9NUG4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| positive regulation of fibroblast growth factor production |
| regulation of fibroblast growth factor production |
| negative regulation of homotypic cell-cell adhesion |
| ventricular trabecula myocardium morphogenesis |
| regulation of homotypic cell-cell adhesion |
| cardiac muscle tissue growth |
| heart growth |
| cardiac atrium morphogenesis |
| heart trabecula morphogenesis |
| cardiac atrium development |
| trabecula morphogenesis |
| ventricular cardiac muscle tissue morphogenesis |
| ventricular cardiac muscle tissue development |
| cardiac muscle tissue morphogenesis |
| cardiac ventricle morphogenesis |
| muscle tissue morphogenesis |
| muscle organ morphogenesis |
| organ growth |
| negative regulation of protein binding |
| cardiac chamber morphogenesis |
| cardiac ventricle development |
| cytokine production |
| cardiac muscle tissue development |
| negative regulation of binding |
| cardiac chamber development |
| negative regulation of cell-cell adhesion |
| regulation of protein binding |
| heart morphogenesis |
| negative regulation of cell adhesion |
| striated muscle tissue development |
| muscle organ development |
| muscle tissue development |
| regulation of binding |
| developmental growth |
| growth |
| regulation of cell-cell adhesion |
| cellular component |
| positive regulation of cytokine production |
| muscle structure development |
| wound healing |
| heart development |
| tissue morphogenesis |
| response to wounding |
| regulation of cell adhesion |
| regulation of cytokine production |
| molecular function |
| circulatory system development |
| animal organ morphogenesis |
| negative regulation of molecular function |
| positive regulation of multicellular organismal process |
| tissue development |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| A-395 10μM R05 exp218 | -1.8 |
| Sucrose 20000μM R06 exp298 | 1.74 |
| Prochlorperazine 5.2μM R02 exp77 | 1.96 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 3246
- Expression level (log2 read counts): 1.02
Expression Distribution
CCM2L Expression in NALM6 Cells: 1.02
