Entrez Summary: Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008].
UniProt Summary: Delivers copper to copper zinc superoxide dismutase (SOD1).
Pfam DomainsGO Terms
Pfam Domains
Sod Cu
HMA
GO Terms
protein maturation by copper ion transfer
superoxide dismutase copper chaperone activity
superoxide dismutase activity
removal of superoxide radicals
cellular response to oxygen radical
cellular response to superoxide
response to superoxide
response to oxygen radical
protein disulfide oxidoreductase activity
superoxide metabolic process
positive regulation of oxidoreductase activity
copper ion binding
cellular oxidant detoxification
regulation of oxidoreductase activity
cellular detoxification
reactive oxygen species metabolic process
detoxification
cellular response to reactive oxygen species
response to reactive oxygen species
cellular response to toxic substance
protein maturation
cellular response to oxidative stress
cadherin binding
response to oxidative stress
response to toxic substance
response to inorganic substance
metal ion transport
cation transport
oxidation-reduction process
cellular response to oxygen-containing compound
ion transport
positive regulation of catalytic activity
response to oxygen-containing compound
cellular response to stress
positive regulation of molecular function
gene expression
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)