UniProt Summary: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Pfam DomainsGO Terms
Pfam Domains
Cadherin C
Cadherin
GO Terms
synaptic cleft
synaptic membrane
cell-cell adhesion mediated by cadherin
synaptic transmission, glutamatergic
catenin complex
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
response to cold
axon terminus
cytoskeletal protein binding
adherens junction organization
cell-cell junction assembly
cell-cell adherens junction
cell-cell junction organization
cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules
response to temperature stimulus
cell junction organization
regulation of synapse organization
regulation of synapse structure or activity
cell-cell adhesion via plasma-membrane adhesion molecules
cadherin binding
glutamatergic synapse
anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
synaptic signaling
cell-cell adhesion
cell surface
calcium ion binding
cell morphogenesis
cellular component morphogenesis
protein homodimerization activity
cell adhesion
biological adhesion
cell-cell signaling
response to abiotic stimulus
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)