Pfam Domains GO Terms
| PMP22 Claudin |
| positive regulation of endothelial cell development |
| positive regulation of establishment of endothelial barrier |
| regulation of establishment of endothelial barrier |
| regulation of endothelial cell development |
| positive regulation of endothelial cell differentiation |
| apicolateral plasma membrane |
| regulation of bicellular tight junction assembly |
| calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules |
| face morphogenesis |
| regulation of endothelial cell differentiation |
| head morphogenesis |
| body morphogenesis |
| face development |
| cortical actin cytoskeleton |
| positive regulation of epithelial cell differentiation |
| outflow tract morphogenesis |
| regulation of cell junction assembly |
| roof of mouth development |
| transforming growth factor beta receptor signaling pathway |
| cell-cell junction assembly |
| bicellular tight junction |
| cell-cell junction organization |
| regulation of epithelial cell differentiation |
| learning |
| cellular response to transforming growth factor beta stimulus |
| response to transforming growth factor beta |
| cell junction assembly |
| cell-cell junction |
| structural molecule activity |
| transmembrane receptor protein serine/threonine kinase signaling pathway |
| cell junction organization |
| heart morphogenesis |
| learning or memory |
| cell-cell adhesion via plasma-membrane adhesion molecules |
| cognition |
| cellular response to growth factor stimulus |
| cell-cell adhesion |
| heart development |
| response to growth factor |
| positive regulation of cell development |
| cell junction |
| behavior |
| enzyme linked receptor protein signaling pathway |
| head development |
| circulatory system development |
| cell adhesion |
| regulation of cell development |
| biological adhesion |
| animal organ morphogenesis |
| regulation of cellular component biogenesis |
| positive regulation of cell differentiation |
| identical protein binding |
| cellular response to endogenous stimulus |
| positive regulation of developmental process |
| nervous system process |
| response to endogenous stimulus |
| regulation of cell differentiation |
| system process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Metformin 40μM R03 exp132 | -2.08 |
| Benzoate 20000μM R08 exp456 | -1.76 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution