CRABP2
Gene Information
- Official Symbol: CRABP2
- Official Name: cellular retinoic acid binding protein 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 1382
- UniProt: P29373
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
Pfam Domains GO Terms
Pfam Domains
| Lipocalin |
GO Terms
| retinoid binding |
| retinoic acid biosynthetic process |
| diterpenoid biosynthetic process |
| retinal binding |
| positive regulation of collateral sprouting |
| retinol binding |
| terpenoid biosynthetic process |
| regulation of retinoic acid receptor signaling pathway |
| regulation of collateral sprouting |
| retinoic acid binding |
| isoprenoid biosynthetic process |
| retinoic acid metabolic process |
| embryonic forelimb morphogenesis |
| forelimb morphogenesis |
| positive regulation of axonogenesis |
| retinoid metabolic process |
| diterpenoid metabolic process |
| regulation of extent of cell growth |
| terpenoid metabolic process |
| cellular hormone metabolic process |
| embryonic limb morphogenesis |
| embryonic appendage morphogenesis |
| isoprenoid metabolic process |
| limb morphogenesis |
| appendage morphogenesis |
| positive regulation of cell morphogenesis involved in differentiation |
| positive regulation of cell growth |
| positive regulation of developmental growth |
| appendage development |
| limb development |
| regulation of cell size |
| regulation of axonogenesis |
| monocarboxylic acid biosynthetic process |
| hormone metabolic process |
| positive regulation of growth |
| positive regulation of neuron projection development |
| carboxylic acid biosynthetic process |
| regulation of cell morphogenesis involved in differentiation |
| organic acid biosynthetic process |
| regulation of developmental growth |
| positive regulation of neuron differentiation |
| regulation of cellular component size |
| positive regulation of cell projection organization |
| epidermis development |
| regulation of cell growth |
| positive regulation of neurogenesis |
| regulation of cell morphogenesis |
| regulation of neuron projection development |
| regulation of anatomical structure size |
| monocarboxylic acid metabolic process |
| regulation of hormone levels |
| positive regulation of nervous system development |
| positive regulation of cell development |
| embryonic morphogenesis |
| lipid biosynthetic process |
| small molecule biosynthetic process |
| regulation of neuron differentiation |
| regulation of growth |
| regulation of plasma membrane bounded cell projection organization |
| regulation of cell projection organization |
| regulation of neurogenesis |
| carboxylic acid metabolic process |
| regulation of nervous system development |
| regulation of cell development |
| cellular lipid metabolic process |
| positive regulation of cell differentiation |
| embryo development |
| oxoacid metabolic process |
| endoplasmic reticulum |
| organic acid metabolic process |
| regulation of anatomical structure morphogenesis |
| positive regulation of cellular component organization |
| lipid metabolic process |
| positive regulation of developmental process |
| generation of neurons |
| neurogenesis |
| positive regulation of multicellular organismal process |
| small molecule metabolic process |
| tissue development |
| regulation of cell differentiation |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 1/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 1/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 6943
- Expression level (log2 read counts): 0.36
Expression Distribution
CRABP2 Expression in NALM6 Cells: 0.36
