DNAJA2

Entrez Summary: N/A
UniProt Summary: Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877). {ECO:0000269|PubMed:24318877}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
QNZ 0.01μM R08 exp439	-2.1
Lead acetate 2000μM R08 exp497	-2.08
CyclicAMP 200μM R08 exp475	-1.95
TNF-alpha 44ng/ml R08 exp533	-1.79
Sulforaphane 9μM R08 exp526 no dilution day6	-1.78
Cyclosporin-A 0.8μM R07 exp347	-1.71
INK128 0.2μM R02 exp70	-1.7
Phorbol-12-myristate-13-acetate 0.57μM R08 exp514	1.8
iCRT14 30μM R08 exp492	1.81
UM0129480 7μM R02 exp85	2.15
Oligomycin-A 2μM R00 exp25	2.45

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution