DNAL4
Gene Information
- Official Symbol: DNAL4
- Official Name: dynein axonemal light chain 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 10126
- UniProt: O96015
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014].
- UniProt Summary: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7304
- Expression level (log2 read counts): 1.78
DNAL4 Expression in NALM6 Cells: 1.78
