ECSCR

Gene Information

Official Symbol: ECSCR
Official Name: endothelial cell surface expressed chemotaxis and apoptosis regulator
Aliases and Previous Symbols: N/A
Entrez ID: 641700
UniProt: Q19T08
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. {ECO:0000269|PubMed:18556573, ECO:0000269|PubMed:19416853}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6

Essentiality Rank: 12383
Expression level (log2 read counts): -7.68

Expression Distribution