UniProt Summary: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
eIF-1a
GO Terms
translation initiation factor activity
translational initiation
translation
peptide biosynthetic process
amide biosynthetic process
peptide metabolic process
cellular amide metabolic process
organonitrogen compound biosynthetic process
cellular nitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
gene expression
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)