Pfam Domains GO Terms
| Fork head |
| establishment of planar polarity of embryonic epithelium |
| regulation of protein polyubiquitination |
| establishment of planar polarity |
| establishment of tissue polarity |
| embryonic camera-type eye morphogenesis |
| embryonic eye morphogenesis |
| embryonic digestive tract development |
| embryonic camera-type eye development |
| morphogenesis of a polarized epithelium |
| genitalia development |
| epithelial to mesenchymal transition |
| roof of mouth development |
| camera-type eye morphogenesis |
| regulation of proteasomal ubiquitin-dependent protein catabolic process |
| digestive tract development |
| digestive system development |
| eye morphogenesis |
| regulation of ubiquitin-dependent protein catabolic process |
| mesenchymal cell differentiation |
| regulation of proteasomal protein catabolic process |
| regulation of protein ubiquitination |
| transcription factor complex |
| regulation of proteolysis involved in cellular protein catabolic process |
| mesenchyme development |
| regulation of protein modification by small protein conjugation or removal |
| regulation of cellular protein catabolic process |
| sensory organ morphogenesis |
| sex differentiation |
| embryonic organ morphogenesis |
| RNA polymerase II regulatory region sequence-specific DNA binding |
| camera-type eye development |
| transcription factor binding |
| extracellular matrix organization |
| eye development |
| visual system development |
| sensory system development |
| regulation of protein catabolic process |
| extracellular structure organization |
| sequence-specific DNA binding |
| reproductive structure development |
| reproductive system development |
| morphogenesis of an epithelium |
| embryonic organ development |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| sensory organ development |
| tissue morphogenesis |
| embryonic morphogenesis |
| developmental process involved in reproduction |
| DNA-binding transcription factor activity |
| regulation of proteolysis |
| regulation of cellular catabolic process |
| tube development |
| animal organ morphogenesis |
| embryo development |
| regulation of catabolic process |
| epithelium development |
| negative regulation of transcription, DNA-templated |
| positive regulation of transcription by RNA polymerase II |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of RNA metabolic process |
| negative regulation of cellular macromolecule biosynthetic process |
| reproductive process |
| reproduction |
| negative regulation of nucleobase-containing compound metabolic process |
| DNA binding |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| positive regulation of transcription, DNA-templated |
| negative regulation of biosynthetic process |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| negative regulation of gene expression |
| positive regulation of RNA metabolic process |
| tissue development |
| regulation of protein modification process |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Dihydrosphingosine 8μM R08 exp476 | -1.9 |
| FTY720 3μM R08 exp483 | 1.87 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution