FOXO6
Gene Information
- Official Symbol: FOXO6
- Official Name: forkhead box O6
- Aliases and Previous Symbols: N/A
- Entrez ID: 100132074
- UniProt: A8MYZ6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Transcriptional activator. {ECO:0000250}.
Pfam Domains GO Terms
Pfam Domains
| Fork head |
GO Terms
| positive regulation of dendritic spine development |
| regulation of dendritic spine development |
| positive regulation of dendrite development |
| insulin receptor signaling pathway |
| memory |
| regulation of dendrite development |
| cellular response to insulin stimulus |
| glucose homeostasis |
| carbohydrate homeostasis |
| response to insulin |
| learning or memory |
| cellular response to peptide hormone stimulus |
| positive regulation of neuron projection development |
| cognition |
| cellular response to peptide |
| transcription factor binding |
| positive regulation of neuron differentiation |
| positive regulation of cell projection organization |
| response to peptide hormone |
| sequence-specific DNA binding |
| positive regulation of neurogenesis |
| response to peptide |
| regulation of neuron projection development |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| positive regulation of nervous system development |
| positive regulation of cell development |
| behavior |
| cellular response to organonitrogen compound |
| cellular response to hormone stimulus |
| regulation of neuron differentiation |
| cellular response to nitrogen compound |
| DNA-binding transcription factor activity |
| regulation of plasma membrane bounded cell projection organization |
| regulation of cell projection organization |
| enzyme linked receptor protein signaling pathway |
| regulation of neurogenesis |
| negative regulation of transcription by RNA polymerase II |
| response to hormone |
| regulation of nervous system development |
| regulation of cell development |
| positive regulation of cell differentiation |
| response to organonitrogen compound |
| cellular response to oxygen-containing compound |
| response to nitrogen compound |
| chemical homeostasis |
| negative regulation of transcription, DNA-templated |
| positive regulation of cellular component organization |
| positive regulation of transcription by RNA polymerase II |
| cellular response to endogenous stimulus |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of RNA metabolic process |
| positive regulation of developmental process |
| nervous system process |
| negative regulation of cellular macromolecule biosynthetic process |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| response to endogenous stimulus |
| negative regulation of cellular biosynthetic process |
| generation of neurons |
| positive regulation of transcription, DNA-templated |
| negative regulation of biosynthetic process |
| response to oxygen-containing compound |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| neurogenesis |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| homeostatic process |
| negative regulation of gene expression |
| positive regulation of RNA metabolic process |
| positive regulation of multicellular organismal process |
| regulation of cell differentiation |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| system process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Cincreasin 100μM R08 exp473 | 1.75 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: N/A
| Tissue | Fraction Of Cell Lines Where Essential |
|---|
Essentiality in NALM6
- Essentiality Rank: 2962
- Expression level (log2 read counts): 4.84
Expression Distribution
FOXO6 Expression in NALM6 Cells: 4.84
