HIST1H2BC
Gene Information
- Official Symbol: H2BC4
- Official Name: H2B clustered histone 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 8347
- UniProt: P62807
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 2149
- Expression level (log2 read counts): -0.13
HIST1H2BC Expression in NALM6 Cells: -0.13
