UniProt Summary: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
Pfam DomainsGO Terms
Pfam Domains
BSP II
GO Terms
bone mineralization
biomineralization
biomineral tissue development
osteoblast differentiation
integrin binding
vesicle
ossification
extracellular matrix organization
extracellular structure organization
positive regulation of cell adhesion
cellular response to growth factor stimulus
response to growth factor
regulation of cell adhesion
molecular function
cell adhesion
biological adhesion
extracellular space
tissue development
extracellular region
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)