IGLL5
Gene Information
- Official Symbol: IGLL5
- Official Name: immunoglobulin lambda like polypeptide 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 100423062
- UniProt: B9A064
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| C1-set |
| C2-set 2 |
GO Terms
| immunoglobulin complex, circulating |
| immunoglobulin receptor binding |
| phagocytosis, recognition |
| B cell receptor signaling pathway |
| phagocytosis, engulfment |
| plasma membrane invagination |
| antigen binding |
| membrane invagination |
| complement activation, classical pathway |
| positive regulation of B cell activation |
| humoral immune response mediated by circulating immunoglobulin |
| complement activation |
| immunoglobulin mediated immune response |
| regulation of B cell activation |
| B cell mediated immunity |
| cell recognition |
| lymphocyte mediated immunity |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
| antigen receptor-mediated signaling pathway |
| phagocytosis |
| defense response to bacterium |
| humoral immune response |
| positive regulation of lymphocyte activation |
| external side of plasma membrane |
| positive regulation of leukocyte activation |
| positive regulation of cell activation |
| immune response-activating cell surface receptor signaling pathway |
| immune response-regulating cell surface receptor signaling pathway |
| regulation of lymphocyte activation |
| endocytosis |
| immune response-activating signal transduction |
| immune response-regulating signaling pathway |
| regulation of leukocyte activation |
| adaptive immune response |
| activation of immune response |
| regulation of cell activation |
| import into cell |
| response to bacterium |
| leukocyte mediated immunity |
| innate immune response |
| membrane organization |
| positive regulation of immune response |
| defense response to other organism |
| immune effector process |
| positive regulation of immune system process |
| regulation of immune response |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| regulation of immune system process |
| immune response |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Losmapimod 1μM R07 exp376 | 1.82 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 18170
- Expression level (log2 read counts): 6.89
Expression Distribution
IGLL5 Expression in NALM6 Cells: 6.89
