Entrez Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1). This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic cognitive disability. [provided by RefSeq, Jul 2008].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
TIR
GO Terms
interleukin-1, type II, blocking receptor activity
interleukin-1 receptor activity
regulation of presynapse assembly
regulation of presynapse organization
regulation of synapse assembly
regulation of synapse organization
regulation of synapse structure or activity
glutamatergic synapse
cytokine-mediated signaling pathway
regulation of nervous system development
regulation of cellular component biogenesis
central nervous system development
cellular response to cytokine stimulus
response to cytokine
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)