Pfam Domains GO Terms
| PH |
| Kinesin |
| FHA |
| DUF3694 |
| KIF1B |
| response to rotenone |
| anterograde neuronal dense core vesicle transport |
| retrograde neuronal dense core vesicle transport |
| dense core granule localization |
| dense core granule cytoskeletal transport |
| dense core granule transport |
| neuron-neuron synaptic transmission |
| secretory granule localization |
| response to insecticide |
| retrograde axonal transport |
| establishment of mitochondrion localization, microtubule-mediated |
| mitochondrion transport along microtubule |
| establishment of mitochondrion localization |
| ATP-dependent microtubule motor activity, plus-end-directed |
| microtubule associated complex |
| neuromuscular synaptic transmission |
| kinesin binding |
| anterograde axonal transport |
| vesicle transport along microtubule |
| lysosome localization |
| mitochondrion localization |
| vesicle cytoskeletal trafficking |
| cellular response to nerve growth factor stimulus |
| response to nerve growth factor |
| kinesin complex |
| axonal transport |
| axon cytoplasm |
| scaffold protein binding |
| axo-dendritic transport |
| microtubule motor activity |
| organelle transport along microtubule |
| kinase binding |
| response to antineoplastic agent |
| cytoplasmic vesicle membrane |
| cytosolic transport |
| transport along microtubule |
| establishment of vesicle localization |
| cytoskeleton-dependent intracellular transport |
| microtubule-based transport |
| vesicle localization |
| response to ketone |
| protein localization to cell periphery |
| ATPase activity |
| microtubule binding |
| cytoplasmic vesicle |
| microtubule-based movement |
| axon |
| microtubule |
| neuron projection |
| establishment of organelle localization |
| anterograde trans-synaptic signaling |
| chemical synaptic transmission |
| dendrite |
| trans-synaptic signaling |
| synaptic signaling |
| cellular response to growth factor stimulus |
| response to toxic substance |
| response to growth factor |
| organelle localization |
| microtubule-based process |
| response to organic cyclic compound |
| apoptotic process |
| response to drug |
| programmed cell death |
| cell death |
| cell-cell signaling |
| cellular response to endogenous stimulus |
| mitochondrion |
| response to endogenous stimulus |
| ATP binding |
| intracellular transport |
| movement of cell or subcellular component |
| response to oxygen-containing compound |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of localization in cell |
| vesicle-mediated transport |
| positive regulation of gene expression |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution