Pfam Domains GO Terms
| Methyltransf 16 |
| hormone-mediated apoptotic signaling pathway |
| protein-lysine N-methyltransferase activity |
| regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| cellular response to dexamethasone stimulus |
| response to dexamethasone |
| cellular response to glucocorticoid stimulus |
| heat shock protein binding |
| cellular response to corticosteroid stimulus |
| regulation of release of sequestered calcium ion into cytosol |
| peptidyl-lysine methylation |
| cellular response to ketone |
| response to antineoplastic agent |
| regulation of calcium ion transport into cytosol |
| skeletal muscle tissue development |
| regulation of sequestering of calcium ion |
| skeletal muscle organ development |
| protein alkylation |
| protein methylation |
| response to glucocorticoid |
| regulation of calcium ion transmembrane transport |
| response to corticosteroid |
| hormone-mediated signaling pathway |
| cellular response to xenobiotic stimulus |
| cellular response to steroid hormone stimulus |
| response to ketone |
| regulation of calcium ion transport |
| macromolecule methylation |
| apoptotic signaling pathway |
| striated muscle tissue development |
| muscle organ development |
| muscle tissue development |
| response to xenobiotic stimulus |
| methylation |
| peptidyl-lysine modification |
| response to steroid hormone |
| regulation of cation transmembrane transport |
| regulation of metal ion transport |
| cellular response to drug |
| muscle structure development |
| regulation of ion transmembrane transport |
| cellular response to lipid |
| cellular response to organic cyclic compound |
| regulation of transmembrane transport |
| protein-containing complex |
| cellular response to hormone stimulus |
| regulation of ion transport |
| response to lipid |
| peptidyl-amino acid modification |
| response to hormone |
| regulation of cellular localization |
| response to organic cyclic compound |
| apoptotic process |
| response to drug |
| programmed cell death |
| cellular response to oxygen-containing compound |
| cell death |
| cellular response to endogenous stimulus |
| response to endogenous stimulus |
| response to oxygen-containing compound |
| tissue development |
| regulation of transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| HMS-I1 1μM R01 exp46 | -2.12 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution