Entrez Summary: Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
UniProt Summary: Component of the elastin-associated microfibrils.
Pfam DomainsGO Terms
Pfam Domains
MAGP
GO Terms
post-embryonic eye morphogenesis
post-embryonic animal organ morphogenesis
microfibril
post-embryonic animal morphogenesis
post-embryonic animal organ development
embryonic eye morphogenesis
post-embryonic development
positive regulation of cold-induced thermogenesis
extracellular matrix structural constituent
regulation of cold-induced thermogenesis
eye morphogenesis
sensory organ morphogenesis
embryonic organ morphogenesis
extracellular matrix organization
eye development
visual system development
collagen-containing extracellular matrix
sensory system development
extracellular structure organization
embryonic organ development
sensory organ development
embryonic morphogenesis
animal organ morphogenesis
embryo development
positive regulation of multicellular organismal process
extracellular region
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)