Pfam Domains GO Terms
| LIM |
| DUF3585 |
| CAMSAP CH |
| CH |
| slow endocytic recycling |
| protein localization to endosome |
| plasma membrane tubulation |
| phosphatidic acid binding |
| retrograde transport, endosome to plasma membrane |
| endocytic recycling |
| cellular response to nerve growth factor stimulus |
| response to nerve growth factor |
| extrinsic component of membrane |
| recycling endosome membrane |
| vesicle-mediated transport to the plasma membrane |
| plasma membrane organization |
| late endosome membrane |
| late endosome |
| Rab GTPase binding |
| protein targeting to membrane |
| trans-Golgi network |
| endosomal transport |
| receptor-mediated endocytosis |
| early endosome |
| establishment of protein localization to membrane |
| cadherin binding |
| protein targeting |
| endomembrane system organization |
| protein localization to membrane |
| cellular response to growth factor stimulus |
| response to growth factor |
| endocytosis |
| neuron projection development |
| import into cell |
| protein localization to organelle |
| neuron development |
| membrane organization |
| intracellular protein transport |
| neuron differentiation |
| identical protein binding |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| cellular response to endogenous stimulus |
| response to endogenous stimulus |
| protein transport |
| intracellular transport |
| generation of neurons |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| neurogenesis |
| cell development |
| establishment of localization in cell |
| nitrogen compound transport |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Dimethyloxaloylglycine 100μM R05 exp229 | 1.84 |
| Gene | Correlation |
|---|---|
| HGC6.3 | 0.473 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution