Pfam Domains GO Terms
| Mab-21 |
| positive regulation of mitochondrial fission |
| mitochondrial fusion |
| mitochondrial fission |
| regulation of mitochondrial fission |
| positive regulation of protein targeting to membrane |
| regulation of protein targeting to membrane |
| ADP binding |
| GDP binding |
| regulation of protein targeting |
| organelle fusion |
| peroxisome |
| positive regulation of mitochondrion organization |
| positive regulation of protein localization to membrane |
| positive regulation of intracellular protein transport |
| mitochondrial outer membrane |
| regulation of mitochondrion organization |
| regulation of protein localization to membrane |
| positive regulation of intracellular transport |
| regulation of intracellular protein transport |
| organelle fission |
| positive regulation of cellular protein localization |
| regulation of intracellular transport |
| positive regulation of protein transport |
| mitochondrion organization |
| positive regulation of establishment of protein localization |
| regulation of cellular protein localization |
| positive regulation of organelle organization |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of cellular localization |
| positive regulation of transport |
| regulation of protein localization |
| regulation of anatomical structure morphogenesis |
| identical protein binding |
| positive regulation of cellular component organization |
| mitochondrion |
| regulation of organelle organization |
| positive regulation of developmental process |
| regulation of transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| HMS-I1 10μM R06 exp256 | -2.11 |
| Etoposide 0.3μM R05 exp199 | -1.81 |
| DABN 20μM R00 exp17 | -1.75 |
| Parthenolide 2.5μM R05 exp238 | -1.74 |
| Lead acetate 2000μM R08 exp498 no dilution day6 | -1.73 |
| Tanespimycin 14μM R08 exp527 | 1.77 |
| Gene | Correlation |
|---|---|
| PRIM1 | 0.537 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 1/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 1/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution