Entrez Summary: This gene encodes the auxiliary subunit of the heteromeric N-terminal acetyltransferase B complex. This complex acetylates methionine residues that are followed by acidic or asparagine residues.[provided by RefSeq, Mar 2010].
UniProt Summary: Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp-Glu. May play a role in normal cell-cycle progression. {ECO:0000269|PubMed:18570629}.
Pfam DomainsGO Terms
Pfam Domains
NatB MDM20
GO Terms
NatB complex
N-terminal peptidyl-methionine acetylation
peptide alpha-N-acetyltransferase activity
peptidyl-methionine modification
N-terminal protein amino acid acetylation
N-terminal protein amino acid modification
protein acetylation
protein acylation
protein maturation
peptidyl-amino acid modification
Golgi apparatus
gene expression
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)