UniProt Summary: May have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241). {ECO:0000269|PubMed:19011241, ECO:0000269|PubMed:24556617}.
Pfam DomainsGO Terms
Pfam Domains
Acetyltransf 1
GO Terms
peptidyl-lysine N6-acetylation
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor