Entrez Summary: The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2012].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
AbfB
VWD
C8
TIL
GO Terms
alpha-L-arabinofuranosidase activity
L-arabinose metabolic process
arabinose metabolic process
pentose metabolic process
sensory perception of sound
sensory perception of mechanical stimulus
monosaccharide metabolic process
carbohydrate metabolic process
sensory perception
nervous system process
small molecule metabolic process
extracellular region
system process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)