PLVAP

Entrez Summary: N/A
UniProt Summary: Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability. {ECO:0000269|PubMed:15155804}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Brefeldin A 0.02μM R00 exp8	-2.75
Atovaquone 15μM R08 exp451	-1.84
Rifampicin 10μM R00 exp32	-1.82
Dihydrosphingosine 8μM R08 exp476	-1.72
Epigallocatechin gallate 20μM R05 exp230	2.6

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution