PRSS56

Gene Information

Official Symbol: PRSS56
Official Name: serine protease 56
Aliases and Previous Symbols: N/A
Entrez ID: 646960
UniProt: P0CW18
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: This gene encodes a protein that contains a peptidase S1 domain and possesses trypsin-like serine protease activity. The encoded protein may play a role in eye development, and mutations in this gene are a cause of autosomal recessive posterior microphthalmos. [provided by RefSeq, Dec 2011].
UniProt Summary: Serine protease required during eye development. {ECO:0000269|PubMed:21397065}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6

Essentiality Rank: 10542
Expression level (log2 read counts): -7.68

Expression Distribution