RAB41
Gene Information
- Official Symbol: RAB41
- Official Name: RAB41, member RAS oncogene family
- Aliases and Previous Symbols: N/A
- Entrez ID: 347517
- UniProt: Q5JT25
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010].
- UniProt Summary: Required for normal Golgi ribbon organization and ER-to- Golgi trafficking. {ECO:0000269|PubMed:23936529}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7036
- Expression level (log2 read counts): -1.53
RAB41 Expression in NALM6 Cells: -1.53
