Pfam Domains GO Terms
| RAMP |
| calcitonin gene-related peptide binding |
| CGRP receptor complex |
| amylin receptor complex 1 |
| calcitonin gene-related peptide receptor signaling pathway |
| calcitonin gene-related peptide receptor activity |
| amylin receptor activity |
| amylin receptor signaling pathway |
| calcitonin family receptor signaling pathway |
| positive regulation of protein glycosylation |
| regulation of protein glycosylation |
| positive regulation of glycoprotein biosynthetic process |
| positive regulation of glycoprotein metabolic process |
| coreceptor activity |
| regulation of glycoprotein biosynthetic process |
| regulation of glycoprotein metabolic process |
| receptor internalization |
| cell |
| receptor metabolic process |
| adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| regulation of G protein-coupled receptor signaling pathway |
| cAMP-mediated signaling |
| cyclic-nucleotide-mediated signaling |
| protein localization to plasma membrane |
| receptor complex |
| adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| protein localization to cell periphery |
| receptor-mediated endocytosis |
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| calcium ion transport |
| divalent metal ion transport |
| divalent inorganic cation transport |
| angiogenesis |
| second-messenger-mediated signaling |
| blood vessel morphogenesis |
| protein localization to membrane |
| blood vessel development |
| vasculature development |
| cardiovascular system development |
| endocytosis |
| cellular response to hormone stimulus |
| cell surface |
| metal ion transport |
| tube morphogenesis |
| import into cell |
| cation transport |
| tube development |
| circulatory system development |
| anatomical structure formation involved in morphogenesis |
| response to hormone |
| intracellular protein transport |
| cellular response to endogenous stimulus |
| positive regulation of protein modification process |
| G protein-coupled receptor signaling pathway |
| ion transport |
| integral component of plasma membrane |
| response to endogenous stimulus |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| establishment of protein localization |
| intracellular signal transduction |
| positive regulation of protein metabolic process |
| establishment of localization in cell |
| regulation of protein modification process |
| nitrogen compound transport |
| positive regulation of macromolecule biosynthetic process |
| vesicle-mediated transport |
| positive regulation of cellular biosynthetic process |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Aphidicolin 0.04μM R06 exp263 | -1.94 |
| Q15 1 to 2μM on day4 R04 exp164 | -1.73 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution