RNF19B
Gene Information
- Official Symbol: RNF19B
- Official Name: ring finger protein 19B
- Aliases and Previous Symbols: N/A
- Entrez ID: 127544
- UniProt: Q6ZMZ0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| IBR |
GO Terms
| cytolytic granule |
| ubiquitin conjugating enzyme binding |
| protein autoubiquitination |
| ubiquitin binding |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| positive regulation of ubiquitin-dependent protein catabolic process |
| positive regulation of proteasomal protein catabolic process |
| ubiquitin ligase complex |
| positive regulation of proteolysis involved in cellular protein catabolic process |
| regulation of proteasomal ubiquitin-dependent protein catabolic process |
| positive regulation of cellular protein catabolic process |
| regulation of ubiquitin-dependent protein catabolic process |
| regulation of proteasomal protein catabolic process |
| regulation of proteolysis involved in cellular protein catabolic process |
| positive regulation of protein catabolic process |
| ubiquitin protein ligase activity |
| regulation of cellular protein catabolic process |
| protein polyubiquitination |
| positive regulation of proteolysis |
| positive regulation of cellular catabolic process |
| regulation of protein catabolic process |
| positive regulation of catabolic process |
| ubiquitin-dependent protein catabolic process |
| modification-dependent protein catabolic process |
| modification-dependent macromolecule catabolic process |
| proteolysis involved in cellular protein catabolic process |
| adaptive immune response |
| cellular protein catabolic process |
| protein catabolic process |
| protein ubiquitination |
| regulation of proteolysis |
| protein modification by small protein conjugation |
| regulation of cellular catabolic process |
| cellular macromolecule catabolic process |
| endoplasmic reticulum membrane |
| protein modification by small protein conjugation or removal |
| regulation of catabolic process |
| endoplasmic reticulum |
| macromolecule catabolic process |
| organonitrogen compound catabolic process |
| proteolysis |
| positive regulation of cellular protein metabolic process |
| positive regulation of protein metabolic process |
| organic substance catabolic process |
| cellular catabolic process |
| immune response |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 12670
- Expression level (log2 read counts): 3.62
Expression Distribution
RNF19B Expression in NALM6 Cells: 3.62
