SLC30A7
Gene Information
- Official Symbol: SLC30A7
- Official Name: solute carrier family 30 member 7
- Aliases and Previous Symbols: N/A
- Entrez ID: 148867
- UniProt: Q8NEW0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity). {ECO:0000250, ECO:0000269|PubMed:15276077, ECO:0000269|PubMed:15994300}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14915
- Expression level (log2 read counts): 6.11
SLC30A7 Expression in NALM6 Cells: 6.11
