SLC37A1
Gene Information
- Official Symbol: SLC37A1
- Official Name: solute carrier family 37 member 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 54020
- UniProt: P57057
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene localizes to the endoplasmic reticulum (ER) membrane. This protein translocates glucose-6-phosphate from the cytoplasm into the lumen of the ER for hydrolysis into glucose by another ER membrane protein. This gene is a member of the solute carrier 37 gene family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].
- UniProt Summary: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6- phosphatase. May not play a role in homeostatic regulation of blood glucose levels. {ECO:0000269|PubMed:21949678}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7751
- Expression level (log2 read counts): 2.86
SLC37A1 Expression in NALM6 Cells: 2.86
