Pfam Domains GO Terms
| exocytic insertion of neurotransmitter receptor to postsynaptic membrane |
| synaptic vesicle fusion to presynaptic active zone membrane |
| vesicle fusion to plasma membrane |
| synaptic vesicle priming |
| BLOC-1 complex |
| neurotransmitter receptor transport to plasma membrane |
| neurotransmitter receptor transport to postsynaptic membrane |
| establishment of protein localization to postsynaptic membrane |
| SNAP receptor activity |
| hippocampal mossy fiber to CA3 synapse |
| neurotransmitter receptor transport |
| protein localization to postsynaptic membrane |
| receptor localization to synapse |
| long-term synaptic potentiation |
| regulation of postsynaptic membrane neurotransmitter receptor levels |
| SNARE complex |
| syntaxin binding |
| protein localization to synapse |
| synaptic vesicle exocytosis |
| exocytic process |
| synaptic vesicle membrane |
| vesicle fusion |
| organelle membrane fusion |
| vesicle-mediated transport to the plasma membrane |
| organelle fusion |
| signal release from synapse |
| neurotransmitter secretion |
| synaptic vesicle cycle |
| vesicle-mediated transport in synapse |
| membrane fusion |
| positive regulation of synaptic transmission |
| signal release |
| neurotransmitter transport |
| regulation of synaptic plasticity |
| protein localization to cell periphery |
| postsynaptic density |
| protein-containing complex localization |
| establishment of protein localization to membrane |
| vesicle organization |
| glutamatergic synapse |
| regulation of neurotransmitter levels |
| neuronal cell body |
| chemical synaptic transmission |
| dendrite |
| anterograde trans-synaptic signaling |
| trans-synaptic signaling |
| modulation of chemical synaptic transmission |
| regulation of trans-synaptic signaling |
| synaptic signaling |
| protein localization to membrane |
| perinuclear region of cytoplasm |
| regulated exocytosis |
| exocytosis |
| cellular protein-containing complex assembly |
| membrane organization |
| secretion by cell |
| export from cell |
| cell-cell signaling |
| secretion |
| protein transport |
| peptide transport |
| protein-containing complex assembly |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| positive regulation of cell communication |
| positive regulation of signaling |
| establishment of localization in cell |
| nitrogen compound transport |
| protein-containing complex subunit organization |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Gene | Correlation |
|---|---|
| RRM1 | 0.463 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution