Pfam Domains GO Terms
| HYR |
| Sushi |
| negative regulation of cell proliferation involved in contact inhibition |
| contact inhibition |
| positive regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| phagolysosome assembly |
| phagosome maturation |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| positive regulation of extrinsic apoptotic signaling pathway |
| lysosome organization |
| lytic vacuole organization |
| autophagosome |
| vacuole organization |
| extracellular matrix structural constituent |
| regulation of extrinsic apoptotic signaling pathway |
| positive regulation of apoptotic signaling pathway |
| response to endoplasmic reticulum stress |
| process utilizing autophagic mechanism |
| autophagy |
| vesicle organization |
| phagocytosis |
| collagen-containing extracellular matrix |
| regulation of apoptotic signaling pathway |
| cell surface |
| positive regulation of apoptotic process |
| positive regulation of programmed cell death |
| negative regulation of cell population proliferation |
| positive regulation of cell death |
| organelle assembly |
| cell adhesion |
| biological adhesion |
| endoplasmic reticulum |
| regulation of apoptotic process |
| regulation of programmed cell death |
| regulation of cell population proliferation |
| positive regulation of signal transduction |
| regulation of cell death |
| cellular response to stress |
| cellular catabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| vesicle-mediated transport |
| membrane |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/26 |
| bone | 0/26 |
| breast | 0/30 |
| central nervous system | 0/49 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/11 |
| fibroblast | 0/1 |
| gastric | 0/14 |
| kidney | 0/18 |
| liver | 0/19 |
| lung | 0/72 |
| lymphocyte | 0/16 |
| ovary | 0/25 |
| pancreas | 0/22 |
| peripheral nervous system | 0/15 |
| plasma cell | 0/12 |
| prostate | 0/1 |
| skin | 0/20 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/28 |
| uterus | 0/5 |
Expression Distribution