STX12
Gene Information
- Official Symbol: STX12
- Official Name: syntaxin 12
- Aliases and Previous Symbols: N/A
- Entrez ID: 23673
- UniProt: Q86Y82
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:G3V7P1}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15219
- Expression level (log2 read counts): 4.8
STX12 Expression in NALM6 Cells: 4.8
