UniProt Summary: Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity). {ECO:0000250|UniProtKB:Q924B5, ECO:0000250|UniProtKB:Q9JMI7}.
Pfam DomainsGO Terms
Pfam Domains
UPAR LY6
GO Terms
regulation of flagellated sperm motility
regulation of cilium-dependent cell motility
anchored component of plasma membrane
binding of sperm to zona pellucida
sperm-egg recognition
cell-cell recognition
sperm motility
flagellated sperm motility
acrosomal vesicle
cilium or flagellum-dependent cell motility
cilium-dependent cell motility
single fertilization
regulation of reproductive process
fertilization
membrane raft
cell recognition
sexual reproduction
regulation of cell motility
regulation of locomotion
multi-organism reproductive process
regulation of cellular component movement
cell motility
localization of cell
locomotion
reproductive process
reproduction
movement of cell or subcellular component
extracellular region
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)