THBS2
Gene Information
- Official Symbol: THBS2
- Official Name: thrombospondin 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 7058
- UniProt: P35442
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008].
- UniProt Summary: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. {ECO:0000269|PubMed:20714802}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15741
- Expression level (log2 read counts): 0.53
THBS2 Expression in NALM6 Cells: 0.53
