UniProt Summary: Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception. {ECO:0000250|UniProtKB:Q8C8S3}.
Pfam DomainsGO Terms
Pfam Domains
Frag1
GO Terms
proprioception
mechanosensitive ion channel activity
neuromuscular process controlling posture
cellular response to mechanical stimulus
neuromuscular process
response to mechanical stimulus
lysosome
lysosomal membrane
cellular response to abiotic stimulus
cellular response to environmental stimulus
regulation of autophagy
cellular response to external stimulus
regulation of cellular catabolic process
sensory perception
regulation of catabolic process
response to abiotic stimulus
transmembrane transport
nervous system process
integral component of plasma membrane
system process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)