AGGF1

Gene Information
  • Official Symbol: AGGF1
  • Official Name: angiogenic factor with G-patch and FHA domains 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 55109
  • UniProt: Q8N302
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010].
  • UniProt Summary: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. {ECO:0000269|PubMed:14961121}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 19069
  • Expression level (log2 read counts): 5.46

Expression Distribution

  • Last modified: 2025/12/10 20:19
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