ANKRD54

Entrez Summary: N/A
UniProt Summary: Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Q15 1 to 2μM on day4 R04 exp164	-1.7
PNU96415E 10μM R03 exp145	1.82

Ank 2
Ank

protein kinase regulator activity
positive regulation of erythrocyte differentiation
regulation of erythrocyte differentiation
positive regulation of myeloid cell differentiation
midbody
positive regulation of hemopoiesis
regulation of myeloid cell differentiation
nucleocytoplasmic transport
protein-containing complex binding
nuclear transport
regulation of hemopoiesis
regulation of protein kinase activity
regulation of kinase activity
positive regulation of cell differentiation
regulation of transferase activity
positive regulation of immune system process
positive regulation of developmental process
regulation of protein phosphorylation
intracellular transport
regulation of phosphorylation
regulation of immune system process
positive regulation of multicellular organismal process
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of cell differentiation
regulation of intracellular signal transduction
establishment of localization in cell
regulation of protein modification process