ARL8A

Entrez Summary: N/A
UniProt Summary: May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

spindle midzone
vacuolar membrane
beta-tubulin binding
alpha-tubulin binding
anterograde axonal transport
axonal transport
axon cytoplasm
azurophil granule membrane
ficolin-1-rich granule membrane
axo-dendritic transport
late endosome membrane
transport along microtubule
midbody
cytoskeleton-dependent intracellular transport
microtubule-based transport
synapse
microtubule-based movement
chromosome segregation
lysosomal membrane
GTPase activity
GTP binding
neutrophil degranulation
neutrophil activation involved in immune response
cell division
neutrophil mediated immunity
neutrophil activation
granulocyte activation
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
cell junction
myeloid leukocyte activation
leukocyte activation involved in immune response
cell activation involved in immune response
microtubule-based process
regulated exocytosis
leukocyte mediated immunity
exocytosis
leukocyte activation
secretion by cell