BFSP1

Gene Information
  • Official Symbol: BFSP1
  • Official Name: beaded filament structural protein 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 631
  • UniProt: Q12934
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a lens-specific intermediate filament-like protein named filensin. The encoded protein is expressed in lens fiber cells after differentiation has begun. This protein functions as a component of the beaded filament which is a cytoskeletal structure found in lens fiber cells. Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 10774
  • Expression level (log2 read counts): 0.12

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1