BTBD3

Entrez Summary: N/A
UniProt Summary: Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
A-395 10μM R05 exp218	1.7
Cryptotanshinone 12μM R05 exp227	1.88

dendrite morphogenesis
dendrite development
cerebral cortex development
pallium development
telencephalon development
forebrain development
cell morphogenesis involved in neuron differentiation
neuron projection morphogenesis
plasma membrane bounded cell projection morphogenesis
cell projection morphogenesis
cell part morphogenesis
cell morphogenesis involved in differentiation
neuron projection development
cell morphogenesis
brain development
head development
neuron development
cellular component morphogenesis
central nervous system development
neuron differentiation
plasma membrane bounded cell projection organization
cell projection organization
generation of neurons
neurogenesis
cell development