C16orf45

Gene Information

Official Symbol: BMERB1
Official Name: bMERB domain containing 1
Aliases and Previous Symbols: N/A
Entrez ID: 89927
UniProt: Q96MC5
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 9618
Expression level (log2 read counts): -0.8

Expression Distribution

Screen	Score
Cincreasin 100μM R08 exp473	-1.74
Isoniazid 100μM R08 exp494	1.78
35°C R06 exp302	1.87

negative regulation of cell motility involved in cerebral cortex radial glia guided migration
negative regulation of glial cell migration
layer formation in cerebral cortex
regulation of glial cell migration
telencephalon glial cell migration
cerebral cortex radial glia guided migration
negative regulation of microtubule depolymerization
cerebral cortex radially oriented cell migration
regulation of microtubule depolymerization
glial cell migration
negative regulation of microtubule polymerization or depolymerization
negative regulation of gliogenesis
cerebral cortex cell migration
telencephalon cell migration
negative regulation of protein depolymerization
forebrain cell migration
negative regulation of protein complex disassembly
regulation of microtubule polymerization or depolymerization
regulation of protein depolymerization
regulation of protein complex disassembly
regulation of gliogenesis
cerebral cortex development
negative regulation of supramolecular fiber organization
negative regulation of cytoskeleton organization
microtubule cytoskeleton
pallium development
regulation of microtubule cytoskeleton organization
gliogenesis
regulation of microtubule-based process
telencephalon development
negative regulation of cell migration
negative regulation of cell motility
negative regulation of neurogenesis
negative regulation of cellular component movement
negative regulation of nervous system development
negative regulation of locomotion
negative regulation of cell development
regulation of supramolecular fiber organization
negative regulation of organelle organization
forebrain development